Author

Amanda M. Gleixner

University of PittsburghORCID 0000-0001-8241-8408Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Christopher J. DonnellyiD· 2 shared Cristian A. BergmanniD· 2 shared Jessica MerjaneiD· 2 shared Jocelyn C. MaunaiD· 2 shared Alessandra ChesiiD· 1 shared Anastasia C. MurthyiD· 1 shared Ashleigh SmirnoviD· 1 shared Bede PortziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

Christopher J. DonnellyORCID

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2 papers

Recent·Most cited

BiochemistryMolecular CellPeer-reviewedJan 1, 2026

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains

Lin Guo, Jacob R. Mann, Jocelyn C. Mauna…·James Shorter

The paper identifies short RNAs that prevent and reverse pathological fibrillization of RNA-binding proteins like FUS and TDP-43, showing therapeutic potential for ALS/FTD.

25 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintApr 7, 2025

Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD

Longxin Xie, Yuehua Zhu, Bryan T. Hurtle…·Christopher J. Donnelly

The paper identifies context-dependent interactors of TDP-43 that regulate its dysfunction in ALS/FTLD using proximity labeling, mass spectrometry, and snRNA-seq integration.

8 citations

humansnRNA-seq

𝕏 PostBluesky