Author

Yue Yu

Howard Hughes Medical InstituteORCID 0000-0001-8306-4648Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yue Yu5 papers · Hertie Institute for Clinical Brain Research

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Wilfred A. van der DonkiD· 2 shared Dinh Thanh NguyeniD· 1 shared Lingyang ZhuiD· 1 shared Yao OuyangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

Wilfred A. van der DonkORCID

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2 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedJan 19, 2026

Oxidative Peptide Backbone Cleavage by a HEXXH Enzyme During RiPP Biosynthesis

Yao Ouyang, Yue Yu, Lingyang Zhu…·Wilfred A. van der Donk

This study identifies two HEXXH enzymes that catalyze oxidative backbone cleavage in RiPP biosynthesis by recognizing specific peptide motifs.

8 citationstop 1%

bacteria (other)proteomics

𝕏 PostBluesky

BiochemistryACS Central SciencePeer-reviewedJun 3, 2024

PEARL-catalyzed peptide bond formation after chain reversal during the biosynthesis of non-ribosomal peptides

Yue Yu, Wilfred A. van der Donk

This study identifies a lantibiotic dehydratase that catalyzes peptide bond formation in the opposite direction of NRPS and PKS biosynthesis, revealing its role as a separate amide bond-forming machinery.

12 citations

bacteria (other)experimental assay

𝕏 PostBluesky