Author

Fei Guo

Central South UniversityORCID 0000-0001-8346-0798Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Aryan TaheriiD· 1 shared Bharti SingaliD· 1 shared Cheng WangiD· 1 shared Cheng ZhuiD· 1 shared Gaomei Zhao· 1 shared Honglei LiiD· 1 shared Huarui Kang· 1 shared Jawdat Al‐BassamiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Aryan TaheriORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedDec 29, 2025

Cryo-EM structures of the tubulin cofactors reveal the molecular basis for the biogenesis of alpha/beta-tubulin

Aryan Taheri, Zhoaqian Wang, Bharti Singal…·Jawdat Al‐Bassam

The paper determines cryo-EM structures of tubulin cofactors bound to β-tubulin, revealing a vise-like mechanism for GTP-hydrolysis dependent α/β-tubulin biogenesis.

5 citations

cryo-EMexperimental assay

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BioinformaticseLifePeer-reviewedMar 13, 2025

Exploring the repository of de novo designed bifunctional antimicrobial peptides through deep learning

Ruihan Dong, Rongrong Liu, Ziyu Liu…·Cheng Zhu

This paper designs bifunctional antimicrobial peptides using deep learning, discovering 16 peptides with both antibacterial and antiviral activity, including two validated against drug-resistant bacteria and viruses.

4 citations

protein sequencedeep learning

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