Søren Buus

This study identifies linear B-cell epitopes against human coronaviruses using pooled sera from COVID-19 convalescents and pre-pandemic controls, revealing cross-reactivity patterns and epitope distribution across coronavirus proteins.

This study shows that Coxsackievirus B directly kills pancreatic β-cells and elicits weak CD8+ T-cell responses, suggesting vaccination could prevent type 1 diabetes.

This study shows that impaired proinsulin handling in β-cells increases MHC-I bound peptides and activates inflammasomes, potentially contributing to autoimmune diabetes.

The paper integrates immunopeptidomics and immunoinformatics to characterize BoLA-DR antigen presentation and identify CD4 T cell epitopes with high predictive accuracy.

NNAlign_MA deconvolves poly-specific MHC peptidome data to accurately characterize binding motifs and improve T cell epitope predictions.