Alexia Carré

This study shows that Coxsackievirus B3 evades CD8+ T-cell immunity by downregulating HLA Class I and viral peptide presentation, while inducing robust CD4+ T-cell responses and memory formation.

This paper introduces a SILAC-TMT-RTS method to study proteome changes in T cell-cancer cell co-cultures, revealing mechanisms of differential sensitivity to T cell killing.

This study shows that EVs deplete GGA2 in beta cells, causing Golgi acidification and altering the MHC class I immunopeptidome through premature cathepsin activation.

This study shows that IFN-α increases HLA-B-restricted antigen presentation in pancreatic β-cells, potentially influencing T1D pathogenesis.

This study shows that Coxsackievirus B directly kills pancreatic β-cells and elicits weak CD8+ T-cell responses, suggesting vaccination could prevent type 1 diabetes.