Peter W. Nathanielsz

This study computes sex-specific survival curves for 12 nonhuman primate species to characterize aging patterns and provides insights into lifespan and healthspan differences.

This study finds that aging baboons show sex-specific declines in prefrontal cortex mitochondrial bioenergetics, with males experiencing greater ETC activity loss and a link between walking speed and respiration in males.

This study identifies age-related metabolic shifts in baboon hearts that promote glycosaminoglycan accumulation via the hexosamine biosynthetic pathway, preceding cardiac hypertrophy.

This study examines the effects of maternal undernutrition on hepatic mitochondrial function in baboon offspring during aging, finding male-specific increases in mitochondrial bioenergetics without changes in plasma metabolites.

The paper compares mitochondrial bioenergetics and cellular resilience across astrocytes, hepatocytes, and fibroblasts from aged baboons under different stressors.

The paper quantifies age-related changes in regulatory and functional proteins in baboon adrenal zonae, finding decreased ZF function and less marked ZR function with age.

The paper integrates multi-omics data from female baboons to identify age-related molecular changes in the prefrontal cortex, revealing altered signaling pathways and potential biomarkers for age-related cognitive decline.

This study integrates multi-omics data from female nonhuman primates to identify aging-related molecular changes in the liver, revealing age-associated pathways in endoplasmic stress and degradation.

This study evaluates label-free quantification and missing value imputation methods in non-human primate proteomics to improve data quality and analysis.

This study examines how reduced maternal nutrition during pregnancy affects kidney function in nonhuman primates, showing persistent molecular and structural changes that influence responses to a high-fat, high-carbohydrate, high-salt diet.

This study develops pan-primate epigenetic clocks and sex predictors using DNA methylation data from 37 primate species, achieving high accuracy for age estimation across species.

This review summarizes how maternal stress and malnutrition during pregnancy affect structural brain aging and age-related brain disorders in humans.