Author

Christopher L. Berger

University of VermontORCID 0000-0001-8481-3479Unclaimed ORCID profile · follow to get notified of new preprints

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Christopher L. Berger1 paper

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

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Adam G. HendricksiD· 1 shared Daniel BeaudetiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiophysics

Adam G. HendricksORCID

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1 paper

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BiophysicsBiophysical JournalPeer-reviewedFeb 1, 2025

Tau hyperphosphorylation impairs cooperative binding tomicrotubules and perturbs organelle trafficking in neurons

Daniel Beaudet, Christopher L. Berger, Adam G. Hendricks

This study shows that tau hyperphosphorylation disrupts cooperative microtubule binding and impairs lysosome trafficking in neurons, contributing to neurodegeneration.

DOI 10.1016/j.bpj.2024.11.2033

humanproteomics

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