Author

Christopher D. Klocke

Oregon Health & Science UniversityORCID 0000-0001-8528-7781Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Guanming WuiD· 3 shared Andrew AdeyiD· 2 shared Ashley N. AndersoniD· 2 shared Melissa Hirose WongiD· 2 shared Patrick Conley· 2 shared Sidharth K. SenguptaiD· 2 shared Alison H. SkaletiD· 1 shared Amy E. MoraniD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBioinformatics

Guanming WuORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 9, 2023

Identification of Cellular Interactions in the Tumor Immune Microenvironment Underlying CD8 T Cell Exhaustion

Christopher D. Klocke, Amy E. Moran, Andrew Adey…·Guanming Wu

The paper develops a framework to analyze scRNA-seq data and identify gene-regulatory networks linked to CD8 T cell exhaustion in tumor and viral infection contexts.

2 citations

humanscRNA-seq

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Cancer BiologybioRxivPreprintOct 24, 2023

Analysis of uveal melanoma scRNA sequencing data identifies neoplastic-immune hybrid cells that exhibit metastatic potential

Ashley N. Anderson, Patrick Conley, Christopher D. Klocke…·Melissa Hirose Wong

The paper identifies neoplastic-immune hybrid cells in uveal melanoma scRNA-seq data that exhibit metastatic potential through gene expression and ligand-receptor analysis.

6 citations

humanscRNA-seq

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Developmental BiologybioRxivPreprintSep 30, 2022

Dual states of Bmi1-expressing intestinal stem cells drive epithelial development and tissue regeneration

Nicholas R. Smith, Sidharth K. Sengupta, Patrick Conley…·Melissa Hirose Wong

The paper identifies a dual state of Bmi1-expressing intestinal stem cells that drive epithelial development and tissue regeneration through dynamic Wnt signaling.

DOI 10.1101/2022.09.30.509798

mousescRNA-seq

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