Author

Adam M. R. de Graff

ORCID 0000-0001-8529-8587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Corey WeistuchiD· 1 shared David E. MosedaleiD· 1 shared David J. GraingeriD· 1 shared Gábor BalázsiiD· 1 shared Ken A. DilliD· 1 shared Tilly SharpiD· 1 shared Tyler MatsuzakiiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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1 shared paperBiophysics

Corey WeistuchORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJul 16, 2024

Transcriptional drift in aging cells: A global de-controller

Tyler Matsuzaki, Corey Weistuch, Adam M. R. de Graff…·Gábor Balázsi

The paper identifies transcriptional drift in aging C. elegans worms, showing upregulated sensory proteins and downregulated growth/metabolism genes, and proposes a mechanistic model involving ligand binding.

9 citations

C. elegansbulk RNA-seq

𝕏 PostBluesky

PathologybioRxivPreprintMar 19, 2024

The remarkable similarity in the serum proteome between type 2 diabetics and controls

David E. Mosedale, Tilly Sharp, Adam M. R. de Graff, David J. Grainger

This study finds the serum proteome is remarkably similar between type 2 diabetics and controls, with major differences being glycations of abundant proteins and associations between BMI and a ternary complex.

1 citation

humanproteomics

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