Diane S. Lidke

This study shows that allergen valency and epitope arrangement influence FcϵRI aggregation and signaling in mast cells.

This study shows that M2 macrophages in the tumor microenvironment enhance ovarian cancer growth and reduce sensitivity to paclitaxel, and that targeting TAMs with CSF-1R inhibitors can improve treatment outcomes when combined with chemotherapy.

This paper introduces a novel optical design for axial de-scanning in light-sheet microscopy's detection arm, enabling aberration-free, multi-color volumetric imaging without sample translation.

This study combines SiMPull and computational modeling to analyze EGFR phosphorylation dynamics and the effects of mutations and ligands on signaling.