Philippe Cluzel

The paper shows that single-cell growth rates increase with flagellar gene activity, contradicting bulk measurements, and attributes this to inherited growth factors.

The paper shows how inherited flagellar structures coordinate swimming onset in E. coli cells by integrating transcriptional noise and sharpening it into a heritable decision.

The paper studies the mar operon in E. coli using single-cell lineage tracking, revealing inducible memory of promoter activity across generations.

The paper shows that flagellum biosynthesis in E. coli is driven by stochastic transcriptional pulses rather than a deterministic program, revealing a post-translational regulatory mechanism.

The paper identifies codon-dependent noise as a source of cell-to-cell variability in E. coli under amino acid-limited conditions, linking it to translational processes and tRNA dynamics.