Gao Zhang

This study integrates multi-omic data from lung cancer and brain metastases to identify mitochondrial metabolism as a therapeutic target in brain metastases.

This study identifies molecular mechanisms of resistance to immune checkpoint blockade in metastatic melanoma using proteogenomic and spatial analyses of tumor and immune microenvironment data.

This study identifies molecular alterations in oral squamous cell carcinoma linked to lymph node metastasis through multi-omics analysis.

The paper introduces a functional genomic complexity (FGC) score to assess genomic heterogeneity in liver cancer, finding higher FGC correlates with worse prognosis and immune evasion.