Author

Jason N. Crain

University of OxfordORCID 0000-0001-8672-9158Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:human· 1 Assay:multiome· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron P. OwjiiD· 1 shared Amitabha Majumdar· 1 shared Khushbu Agarwal· 1 shared Linda X. PhaniD· 1 shared Mark S.P. SansomiD· 1 shared Martyn WinniD· 1 shared Michael HoptroffiD· 1 shared Morris WaskariD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

Aaron P. OwjiORCID

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2 papers

Recent·Most cited

BiophysicsJournal of Chemical Theory and ComputationPeer-reviewedJan 3, 2025

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel

Linda X. Phan, Aaron P. Owji, Tingting Yang…·Stephen J. Tucker

The paper shows that electronic polarization is essential for accurately simulating Cl- permeation through the hBest1 channel and resolving ion-like densities in cryo-EM structures.

2 citations

humancryo-EM

𝕏 PostBluesky

Molecular BiologyBiophysical JournalPeer-reviewedDec 23, 2021

Small molecules enhance the potency of natural antimicrobial peptides

Valeria Losasso, Khushbu Agarwal, Morris Waskar…·Michael Hoptroff

The paper shows that certain small molecules, like niacinamide, enhance the activity of antimicrobial peptides against Staphylococcus aureus by altering bacterial membrane properties.

14 citations

simulation

𝕏 PostBluesky