Author

Payam Amini

Iran University of Medical SciencesORCID 0000-0001-8675-0045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Irina A DinuiD· 2 shared Saumyadipta PyneiD· 2 shared Erfan GhasemiiD· 1 shared Morteza HajihosseiniiD· 1 shared Paul Calistrate-Petre· 1 shared Sara KhademiourehiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBioinformatics

Irina A DinuORCID

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2 papers

Recent·Most cited

BioinformaticsStatistics in BiosciencesPeer-reviewedMay 7, 2026

Stability and Performance of Linear Combination Tests of Gene Set Enrichment for Multiple Covariance Estimators in Unbalanced Studies

Sara Khademioureh, Payam Amini, Erfan Ghasemi…·Irina A Dinu

This paper evaluates the performance of linear combination tests for gene set enrichment using different covariance estimators in unbalanced studies, finding ridge estimation more reliable for unbalanced designs.

DOI 10.1007/s12561-026-09521-z

bulk RNA-seqstatistical model

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BioinformaticsFrontiers in Cell and Developmental BiologyPeer-reviewedMar 9, 2023

Geographically Weighted Linear Combination Test for Gene Set Analysis of a Continuous Spatial Phenotype as applied to Intratumor Heterogeneity.

Payam Amini, Morteza Hajihosseini, Saumyadipta Pyne, Irina A Dinu

The paper introduces GWLCT, a geographically weighted linear combination test for gene set analysis of continuous spatial phenotypes, showing improved performance in detecting spatially varying gene-set associations in tumor samples.

5 citations

humanspatial transcriptomics

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