Lei Li

In 5-FU-treated mice, oral and intestinal epithelial atrophy stems from p53-linked cell cycle arrest, not apoptosis, while a chemoresistant AP-1/p53 basal cluster expands in tongue.

This paper introduces M3-CAD, a deep learning pipeline for designing multi-mechanism antimicrobial peptides to combat multidrug-resistant organisms, showing effectiveness in a skin wound infection model.

This study evaluates the impact of HRD status on clinical outcomes in Chinese EOC patients undergoing first-line chemotherapy and PARPi maintenance therapy, showing improved PFS and OS in HRD-positive patients.