Milagros Medina

This study investigates the functional plasticity of AIF through dimerization and CHCHD4 interaction states, revealing conformational dynamics and redox regulation.

This paper demonstrates a method to reduce sample consumption in time-resolved serial crystallography by using segmented droplet generation and mix-and-inject approaches for studying NQO1's redox cycle.

This paper identifies Rv3284 (SufEMtb) as a new activator of Mtb's SseA enzyme, revealing a regulatory mechanism that could be targeted for tuberculosis therapy.

This study investigates the role of Tyr126 and Tyr128 in human NQO1 catalysis, showing their critical impact on enzyme activity and non-synchronous catalysis.

This study determines the structure of hNQO1 with NADH using serial crystallography and simulations, showing NADH binding stabilizes the protein and drives functional cooperativity through structural communication.