Author

John M. Leech

University of California, San FranciscoORCID 0000-0001-8766-4915Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Antonin WeckeliD· 2 shared Tiffany C. ScharschmidtiD· 2 shared Adeeb H. Rahmman· 1 shared Ahmed Al-AdhamiiD· 1 shared Alessandro LaganàiD· 1 shared Alexis J. CombesiD· 1 shared Allison E. TammeniD· 1 shared Alyssa Granados· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Antonin WeckelORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 30, 2026

Self-antigen disrupts cDC1 mediated antitumor responses

Victoria P. Schuster, Kasidy Brown, Valentina Laverde…·Megan K. Ruhland

This study shows that self-antigen disrupts cDC1-mediated antitumor responses by altering antigen processing and cross-presentation in dendritic cells.

DOI 10.64898/2026.06.25.734634

mouseimaging

𝕏 PostBluesky

ImmunologyImmunityPeer-reviewedJan 29, 2026

Commensal myeloid crosstalk in neonatal skin regulates cutaneous type 17 inflammation

Miqdad O. Dhariwala, Ricardo O Carale, Andrea M. DeRogatis…·Tiffany C. Scharschmidt

This study shows that commensal microbes in neonatal skin promote immune homeostasis by regulating monocyte accumulation and IL-17A production by T cells.

8 citationstop 1%

mouseexperimental assay

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GenomicsNature CancerPeer-reviewedJan 9, 2026

A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

William Pilcher, Lijun Yao, Edgar Gonzalez‐Kozlova…·Manoj Bhasin

The paper characterizes immune microenvironment dysregulation in multiple myeloma using single-cell data and links it to disease progression and patient outcomes.

37 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky