Author

Donald C. Sheppard

McGill University Health CentreORCID 0000-0001-8877-880XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

François Le MauffiD· 3 shared P. Lynne HowelliD· 3 shared Mario A. VargasiD· 2 shared Roland PfohiD· 2 shared D. RajuiD· 1 shared Daniel J. WozniakiD· 1 shared Daphnée LamarcheiD· 1 shared Erum RazviiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

François Le MauffORCID

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3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedJul 7, 2025

Autoaggregation in Streptococcus intermedius is driven by the Pel polysaccharide

D. Raju, Siobhán A. Turner, Karla Castro…·P. Lynne Howell

This study identifies the Pel polysaccharide as a driver of autoaggregation in S. intermedius, linking it to biofilm formation and increased pathogenicity.

3 citations

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologyJournal of Biological ChemistryPeer-reviewedMar 20, 2025

Structural and functional analysis of Pseudomonas aeruginosa PelA provides insight into the modification of the Pel exopolysaccharide

Jaime C. Van Loon, François Le Mauff, Mario A. Vargas…·P. Lynne Howell

This study determines the structure of PelA and shows it modifies Pel through deacetylation and hydrolysis, with PelAB interaction enhancing deacetylation and guiding export.

4 citations

bacteria (other)experimental assay

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MicrobiologyPLoS PathogensPeer-reviewedJun 18, 2024

CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan

Linda Heilig, Fariha Natasha, Nora Trinks…·Juergen Loeffler

This study identifies galactosaminogalactan as the fungal ligand for CD56 on human NK cells, triggering antifungal responses and immune cell activation.

14 citations

humanproteomics

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