Author

Maria E. Kaufman

Columbia University Irving Medical CenterORCID 0000-0001-8892-0415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alexandre ChlenskiiD· 2 shared Chuan HeiD· 2 shared Kelley MooreiD· 2 shared Mark A. ApplebaumiD· 2 shared Omar R. VayaniiD· 2 shared Ali S. RopriiD· 1 shared Ami V. Desai· 1 shared Andrew A. SprouliD· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Alexandre ChlenskiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeuroscienceJournal of NeurosciencePeer-reviewedNov 22, 2023

ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease

Anne Marie W. Bartosch, Elliot H. H. Youth, Shania Hansen…·Andrew F. Teich

This study shows ZCCHC17 regulates RNA splicing in neurons and its dysfunction contributes to splicing abnormalities in Alzheimer's disease, with potential therapeutic implications.

10 citations

humanstatistical model

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GenomicsPediatric Blood & CancerPeer-reviewedOct 20, 2023

Adrenergic and mesenchymal signatures are identifiable in cell-free DNA and correlate with metastatic disease burden in children with neuroblastoma

Omar R. Vayani, Maria E. Kaufman, Kelley Moore…·Mark A. Applebaum

The paper identifies adrenergic and mesenchymal signatures in cell-free DNA 5-hmC profiles and shows their correlation with metastatic burden in neuroblastoma patients.

15 citations

humanDNA methylation

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Cancer BiologybioRxivPreprintJun 26, 2023

T-cell inflammation is prognostic of survival in patients with high-risk neuroblastoma enriched for an adrenergic signature

Maria E. Kaufman, Omar R. Vayani, Kelley Moore…·Mark A. Applebaum

The paper identifies T-cell inflammation (TCI) as a prognostic marker in high-risk neuroblastoma, showing improved survival in ADRN tumors but not MES tumors.

DOI 10.1101/2023.06.26.546541

humanbulk RNA-seq

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