Martine C. Holst Sørensen

SugarBase identifies microbial nucleotide sugar profiles, revealing species-specific and previously unannotated sugars, and expands antimicrobial targets.

This paper develops campycins, retargeted pyocins that kill Campylobacter jejuni by binding to MOMP, achieving over 3-log reductions under microaerobic conditions.

This study shows Ackermannviridae phages can acquire new tail spike proteins to expand their branched receptor complex, enabling adaptation to new hosts.

The paper isolates and characterizes 28 unique bacteriophages against ESBL/AmpC E. coli, showing they can form broad host range cocktails effective in inhibiting bacterial growth in vitro.

Agtrevirus phage AV101 expresses four unique tail spike proteins that recognize different O-antigens of Extended Spectrum β-lactamase-producing E. coli.

The paper identifies a hybrid receptor binding protein in phage F341 that enables infection of Campylobacter by binding to flagella and lipooligosaccharides, revealing potential for phage resistance mechanisms.