Author

Sarah Kosta

University of KentuckyORCID 0000-0001-8995-7391Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Abbi Hau· 1 shared Adele D’AmicoiD· 1 shared Anders OldforsiD· 1 shared Edmar ZanoteliiD· 1 shared Edoardo MalfattiiD· 1 shared Francesco MuntoniiD· 1 shared Glenn CarringtoniD· 1 shared Hannah F. DugdaleiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Abbi Hau

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1 paper

Recent·Most cited

PhysiologyJCI InsightPeer-reviewedOct 3, 2023

Human light meromyosin mutations linked to skeletal myopathies disrupt the coiled coil structure and myosin head sequestration

Glenn Carrington, Abbi Hau, Sarah Kosta…·Julien Ochala

This study investigates how mutations in MYH7 and MYH2 genes affect myosin structure and function, finding that they disrupt coiled-coil structure and increase ATP consumption without affecting contractile function.

16 citations

humanproteomics

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