Gaëlle Recher

This study shows that iPSC-derived epithelial cortinoids use reversible cytoskeletal instabilities to withstand large deformations during morphogenesis.

The paper develops 3D mammary duct models of healthy and tumoral tissues using a microfluidic co-extrusion platform to better mimic breast tissue architecture and function.

This paper develops a method to assess micro-tissue mechanics non-destructively, revealing that stiffness gradients in the tumour microenvironment slow pressure increase during growth.

The paper studies how cell division affects the extracellular matrix in human colonic epithelium organoids using 4D imaging and Digital Volume Correlation.

The paper introduces an imaging platform for long-term monitoring of multi-cellular assemblies in an incubator, demonstrating its use with hiPSCs and yeast cells.

The paper introduces a bronchioid model using human bronchial stem cells in an alginate scaffold to mimic distal airway structure and function, showing ciliary activity and pathophysiological features.

The paper develops a method to quantify clearing efficiency in 3D cell spheroids using a deep convolutional neural network and local contrast metrics.

This study shows that DUX4 regulates the oocyte-to-embryo transition in humans by activating enhancers and promoting genome reprogramming.

The paper analyzes complement molecule expression and deposition in human pre-implantation embryos, showing complement activation and defense mechanisms at early stages of development.