Author

Dian Ding

Harvard UniversityORCID 0000-0001-9046-7816Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jack W. SzostakiD· 3 shared Christopher E. CarriD· 1 shared Daniel DuzdevichiD· 1 shared Lijun ZhouiD· 1 shared Marco TodiscoiD· 1 shared Seohyun Chris KimiD· 1 shared Stephanie J. ZhangiD· 1 shared Travis WaltoniD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

Jack W. SzostakORCID

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3 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedMay 31, 2024

Diaminopurine in Nonenzymatic RNA Template Copying

Xiwen Jia, Ziyuan Fang, Seohyun Chris Kim…·Jack W. Szostak

This study investigates whether replacing adenine with diaminopurine in nonenzymatic RNA template copying improves efficiency and reduces bias.

5 citations

DNA methylationexperimental assay

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BiochemistryNucleic Acids ResearchPeer-reviewedJan 29, 2024

Transient states during the annealing of mismatched and bulged oligonucleotides

Marco Todisco, Dian Ding, Jack W. Szostak

This study examines how mismatches and bulges in DNA/RNA duplexes affect hybridization kinetics and shows that transient low-specificity states can support prebiotic copying reactions.

18 citations

DNA methylationexperimental assay

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Molecular BiologyNucleic Acids ResearchPeer-reviewedMar 5, 2021

Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension

Daniel Duzdevich, Christopher E. Carr, Dian Ding…·Jack W. Szostak

The paper investigates error frequency in nonenzymatic RNA primer extension by analyzing sequence context and the competition between bridged dinucleotides and mononucleotides.

34 citations

experimental assay

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