Ruanbao Zhou

The paper predicts cyanobacterial diazotrophy using protein-family content and prioritizes candidate protein families for experimental validation.

This paper identifies a novel heterocyst-specific protein secretion pathway in Anabaena by analyzing nitrogen-responsive extracellular proteomes under different nitrogen conditions.

The paper uses live-cell imaging and a homology-aware framework to identify nitrogenase organization in heterocysts and prioritize cyanobacterial condensate candidates.

The paper sequences the genome of heterocysts in Anabaena cylindrica, revealing deletions of six DNA elements and restoration of five genes critical for N2 fixation.

This study shows unicellular cyanobacteria can maintain nitrogenase activity under continuous light and oxygen, challenging previous assumptions about oxygen tolerance in nitrogen fixation.