Author

Christophe de La Roche Saint-André

Centre National de la Recherche ScientifiqueORCID 0000-0001-9079-4892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Vincent GéliiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

2 papers

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedFeb 27, 2026

Aneuploidy alleviates the cell proliferation defect caused by mutations affecting origin licensing in Saccharomyces cerevisiae

Christophe de La Roche Saint-André

The paper shows that aneuploidy in yeast can enhance cell proliferation by extending the G1 phase, compensating for defects in DNA replication licensing.

DOI 10.1371/journal.pgen.1012063

yeastexperimental assay

𝕏 PostBluesky

GeneticsDNA repairPeer-reviewedJun 18, 2021

Set1-dependent H3K4 methylation becomes critical for DNA replication fork progression in response to changes in S phase dynamics in Saccharomyces cerevisiae

Christophe de La Roche Saint-André, Vincent Géli

The paper shows that Set1-dependent H3K4 methylation is critical for DNA replication fork progression when replication forks accelerate due to reduced origin firing in yeast.

10 citations

yeastDNA methylation

𝕏 PostBluesky