Cross-Ancestry Polygenic Risk Scores Enhance Alzheimer's Disease Risk Prediction in Multiethnic Cohorts
Michael C Okorie, Caroline Jonson, Alexis P. Oddi…·for the Alzheimer's Disease Sequencing Project and the Healthy Aging Brain Study—Health Disparities
This paper evaluates cross-ancestry polygenic risk scores (PRS) for Alzheimer's disease across multi-ethnic populations, finding improved predictive accuracy in non-European groups.