Jo Anne Powell‐Coffman

The paper identifies HIF-1 binding sites and hypoxia-responsive genes in C. elegans using gene expression and ChIP-seq analyses, revealing their roles in metabolism and stress response.

The paper examines the gene expression changes in C. elegans mutants with persistent HIF-1 over-activation, revealing shared pathways and functional overlaps with DAF-16 in stress responses.

This study shows that PTTH loss-of-function in Drosophila extends lifespan by repressing NF-κB signaling in oenocytes during metamorphosis.

The paper identifies crosstalk between SKN-1/NRF and HIF-1 in C. elegans, showing SKN-1 inhibits HIF-1 through EGL-9 regulation.