Sabrina M. Huber

The paper improves click-code-seq for mapping DNA oxidation and depurination in human genomes, revealing strand bias in oxidized guanines and apurinic sites.

This paper introduces O6-MeG-seq, a method to map O6-methylguanine at single-nucleotide resolution, and shows MGMT does not preferentially repair O6-MeG based on sequence context or chromatin state.

The paper introduces AQRNA-seq, a method for accurate small RNA quantification, and demonstrates its application to bacterial tRNA pools revealing copy number variation and modification patterns.