Cancer BiologybioRxivPreprint
MYC amplifies mitotic perturbations elicited by LXY18 to enable synthetic lethality
Julia Kalashova, Chenglu Yang, Yan Long…·Dun Yang
This study shows that LXY18 selectively kills MYC-overexpressing cancer cells by inducing mitotic arrest, offering a new approach to target MYC-driven tumors.
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