Author

Gang Lv

ORCID 0000-0002-1310-2087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Dun YangiD· 2 shared Namrta ChoudhryiD· 2 shared Qiong ShiiD· 2 shared Ting ZhangiD· 2 shared Chenglu Yang· 1 shared Duo Yu· 1 shared Hong Liu· 1 shared Hongmei LiiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Dun YangORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 25, 2023

Pharmacokinetics, Tissue Distribution, and Formulation Study of a Small-molecule Inhibitor of MKLP2, LG157

Namrta Choudhry, Jinhua Li, Ting Zhang…·Dun Yang

This study evaluates the drug developability of LG157, a MKLP2 inhibitor, by assessing its pharmacokinetics, tissue distribution, and formulation using SEDDS.

DOI 10.1101/2023.12.25.573327

mouserat

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 7, 2023

MYC amplifies mitotic perturbations elicited by LXY18 to enable synthetic lethality

Julia Kalashova, Chenglu Yang, Yan Long…·Dun Yang

This study shows that LXY18 selectively kills MYC-overexpressing cancer cells by inducing mitotic arrest, offering a new approach to target MYC-driven tumors.

1 citation

humanbulk RNA-seq

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