Elizaveta Elshina

This study shows that fever during influenza A virus infection increases antiviral signaling by promoting aberrant RNA synthesis and innate immune activation.

This study identifies a two-step mechanism by which influenza virus mini viral RNAs (mvRNAs) activate RIG-I through non-canonical transcription and RNA structure-dependent binding.

This study identifies a novel IAV RNA species, capped complementary RNAs (ccRNAs), which hybridize with viral RNA to activate RIG-I, revealing an alternative mechanism for innate immune activation during IAV infection.

This study quantifies influenza virus mini viral RNA (mvRNA) dynamics and subcellular distribution using Cas13, revealing non-random behavior and differences between immunostimulatory and non-immunostimulatory mvRNAs.