Author

Christopher Ritchie

Arc Research InstituteORCID 0000-0001-9432-8602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Benjamin F. CravattiD· 1 shared Evert NjomeniD· 1 shared Lingyin LiiD· 1 shared R. J. M. Chan· 1 shared Sabrina L. ErguniD· 1 shared Stephen R. LynchiD· 1 shared Xujun CaoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Benjamin F. CravattORCID

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1 paper

Recent·Most cited

BiochemistryNature Chemical BiologyPeer-reviewedJul 3, 2025

Human STING oligomer function is governed by palmitoylation of an evolutionarily conserved cysteine

R. J. M. Chan, Xujun Cao, Sabrina L. Ergun…·Lingyin Li

This paper identifies palmitoylation at C64 as critical for preventing unproductive STING oligomerization and shows a peptide inhibitor targeting the oligomerization interface.

38 citationstop 1%

humanproteomics

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