BiochemistryNature Chemical BiologyPeer-reviewed
Human STING oligomer function is governed by palmitoylation of an evolutionarily conserved cysteine
R. J. M. Chan, Xujun Cao, Sabrina L. Ergun…·Lingyin Li
This paper identifies palmitoylation at C64 as critical for preventing unproductive STING oligomerization and shows a peptide inhibitor targeting the oligomerization interface.
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