Author
Seattle Children's Research InstituteORCID 0000-0001-9570-5086Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Brandon S. Maust, Kira A. Griswold, Monique Khim…·Heather B. Jaspan
The paper analyzes Gardnerella prophages and their endolysins, finding clustering of prophage sequences by bacterial species within the genus.
Avery Chiu, Lijun Liu, Steve A. Seibold…·Oluwatoyin Ajibola Asojo
This paper reports the purification, crystallization, and structure of Trichomonas vaginalis pyrophosphate-dependent phosphofructokinase (TvPPi-PFK), revealing its active site and additional ligand-binding sites.
Kenneth Austin, Vincent A Obakachi, Florence Lisa Muzenda…·Graham Chakafana
The paper reports high-resolution structures of T. cruzi glycolytic enzymes and identifies potential inhibitors through structural analysis and virtual screening.
Jillian E. Milanes, Victoria C. Yan, Cong-Dat Pham…·James C. Morris
This paper shows that enolase inhibitors, specifically HEX, are effective against Naegleria fowleri by inhibiting its glycolytic pathway and extending survival in infected rodents.
Kayleigh F. Barrett, Logan M. Tillery, Jenna Goldstein…·Wesley C. Van Voorhis A
The paper reports the structural determination of 19 N. fowleri proteins, identifying potential drug targets with structural differences from human homologs.
Isabelle Q. Phan, Sandhya Subramanian, David E. Kim…·Wesley C. Van Voorhis A
The paper predicts SARS-CoV-2 B-cell epitopes using computational methods and validates them with ELISA, finding two antigens with high sensitivity and specificity for serological diagnosis of COVID-19.