Author
University of WashingtonORCID 0000-0002-5431-3489Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jillian E. Milanes, Victoria C. Yan, Cong-Dat Pham…·James C. Morris
This paper shows that enolase inhibitors, specifically HEX, are effective against Naegleria fowleri by inhibiting its glycolytic pathway and extending survival in infected rodents.
Kayleigh F. Barrett, Logan M. Tillery, Jenna Goldstein…·Wesley C. Van Voorhis A
The paper reports the structural determination of 19 N. fowleri proteins, identifying potential drug targets with structural differences from human homologs.
Isabelle Q. Phan, Sandhya Subramanian, David E. Kim…·Wesley C. Van Voorhis A
The paper predicts SARS-CoV-2 B-cell epitopes using computational methods and validates them with ELISA, finding two antigens with high sensitivity and specificity for serological diagnosis of COVID-19.
Isabelle Q. Phan, Christopher A. Rice, Justin K. Craig…·Peter John Myler
The paper identifies 59 compounds that inhibit Balamuthia mandrillaris growth and reconstructs its transcriptome to determine potential molecular targets for drug development.