Author

April M. Miguez

Georgia Institute of TechnologyORCID 0000-0001-9593-3302Unclaimed ORCID profile · follow to get notified of new preprints

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Systems Biology· 1

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Organism:E. coli· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

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Fernanda PiorinoiD· 1 shared Mark P. StyczynskiiD· 1 shared Yan ZhangiD· 1 shared

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2021-2021 · peak 1/yr

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Fernanda PiorinoORCID

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Systems BiologyACS Synthetic BiologyPeer-reviewedSep 3, 2021

Metabolic Dynamics in Escherichia coli-based Cell-Free Systems

April M. Miguez, Yan Zhang, Fernanda Piorino, Mark P. Styczynski

This study investigates metabolic dynamics in Escherichia coli-based cell-free systems using metabolomics, finding that lysate preparation significantly affects protein yield and metabolic profiles, while endogenous metabolism is resilient to enzymatic perturbations.

23 citations

E. colimetabolomics

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