Maria A. Lagarkova

This study compares chromatin architecture in iPSC-derived neurons to fetal and mature neurons, finding iPSC-derived neurons resemble fetal neurons and have distinct chromatin features.

The paper identifies TP63 and TRIM29 as regulators of enhancer methylation and chromosomal instability in prostate cancer by integrating multi-omics data from The Cancer Genome Atlas.

This study uses patient-derived iPSCs with a GNAO1 variant to show altered neuronal differentiation and function in cortical neurons.

This study shows splicing inhibitors induce DNA repair gene downregulation in cancer cells, creating a vulnerability that can be exploited by combining them with DNA-damaging agents.