Fabio Piano

This study shows avocado-derived compounds alter lipid homeostasis and lipid droplet profiles in C. elegans by disrupting mitochondrial function and lipid metabolism.

This study examines genome evolution in parthenogenetic nematodes, revealing chromosome fusions, rearrangements, and evidence of rare sexual reproduction events.

TeloSearchLR identifies novel telomere repeat motifs using long sequencing reads, improving detection in cases where short-read tools fail.

This study identifies avocado fatty alcohols/acetates (AFAs) as a new class of anthelmintics that target lipid metabolism in parasitic nematodes.

This study investigates the interaction between SARS-CoV-2 Nsp9 and nanobody 2NSP90 using NMR spectroscopy and molecular dynamics simulations, revealing stoichiometry and epitope details.

The paper shows that the Omicron Spike protein's positive electrostatic surface enhances ACE2 binding and antibody evasion, contributing to its higher transmissibility.

The paper identifies LOTR-1, a C. elegans protein with LOTUS and Tudor domains, which interacts with ZNFX-1 to regulate small RNA processing in the germline.

The paper quantifies sex-specific small RNAomes in C. elegans and identifies sex- and tissue-specific differences in RNAi resistance.

The paper investigates piRNA biogenesis in nematodes, showing that piRNA upstream motifs are derived from snRNA promoter elements and that piRNA production depends on RNA polymerase II pausing and chromatin structure.