Emily Flynn

This study compares molecular features of SSc-NSIP and SSc-UIP with IPF, finding shared epithelial changes and distinct fibroblast programs.

The paper identifies CD8+ T cells as key drivers of fibrosis in morphea-spectrum diseases through fibroblast IFN-γ signaling using spatial transcriptomics.

The paper compares mouse and human tumor microenvironments, identifying conserved and species-specific features in immune composition and gene expression programs.

The paper uses single-cell transcriptomics to analyze endometrial cells from endometriosis patients, revealing altered cellular features and immune communication networks across the menstrual cycle.

The paper identifies two immunological subtypes of Sjögren's disease using single-cell RNA sequencing, highlighting distinct IFN-I signatures and transitional B cell characteristics.

This study uses single-cell RNA sequencing of PBMCs from RA patients and controls to identify disease-associated cell subsets and gene signatures linked to RA disease activity.

This study uses single-cell transcriptomics to identify immune dysregulation in JDM, revealing coordinated type I interferon activity and B cell abnormalities.

The paper analyzes smoking and sex effects on gene expression across multiple tissues using public data, identifying tissue-specific and sex-related gene expression changes.

The paper infers sex labels from gene expression data across human and mouse samples and identifies sex bias in drug studies.

This study identifies sex-specific genetic variants and causal links for testosterone using UK Biobank data and Bayesian modeling.

GRep represents gene sets as multivariate Gaussian distributions to improve drug target identification from expression-derived gene sets.