BioinformaticsbioRxivPreprint
Profiling drug sensitivity of leukemic stem cells via bulk-to-single-cell deconvolution
Alexandre Coudray, Romain Forey, Benjamı́n Béjar…·Didier Trono
The paper develops a machine learning framework to estimate cell subtype-specific drug sensitivity from bulk data, applying it to leukemia datasets to identify potential therapeutic targets.
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