Author

Cailean Carter

Quadram InstituteORCID 0000-0001-9809-2465Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Cailean Carter1 paper · University of Birmingham

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:E. coli· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Aldert ZomeriD· 1 shared Alison E. MatheriD· 1 shared Dipali SinghiD· 1 shared Gemma C. LangridgeiD· 1 shared John R. WainiD· 1 shared Sam NooijiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Aldert ZomerORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintDec 5, 2025

MetaPointFinder: Detection of Antimicrobial Resistance-Conferring Point Mutations (ARMs) from Metagenomic Reads

Aldert Zomer, Sam Nooij, Cailean Carter, Alison E. Mather

MetaPointFinder detects antimicrobial resistance-conferring point mutations from metagenomic reads, outperforming existing methods in simulated data.

1 citation

metagenomicsstatistical model

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Systems BiologybioRxivPreprintJul 25, 2025

Genome-scale metabolic modelling of trimethoprim's mode of action reveals free ATP salvaged to restore purine pool

Cailean Carter, Dipali Singh, John R. Wain, Gemma C. Langridge

This study uses genome-scale metabolic modeling to show trimethoprim induces ATP salvage to repair DNA in E. coli when environmental purines are absent, validated by ATP bioluminescence screening.

DOI 10.1101/2025.07.25.666800

E. colimetabolomics

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