Molecular BiologybioRxivPreprint
A bacterial PrimPol-reverse transcriptase hybrid protein has a proofreading exonuclease activity that can be transferred to other reverse transcriptases
4 citations
Author
Hengyi Xu
The University of Texas at AustinORCID 0000-0001-9809-4882Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2019-2025 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 17 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- BiochemistryInstitutional Repositories DataBase (IRDB)Peer-reviewed
Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation
Yingjie Hu, Victor A Lopez, Hengyi Xu…·Vincent S. Tagliabracci
This study identifies C12orf29 as an RNA ligase that ligates tRNA and alters tRNA levels in mice, with structural insights into its catalytic mechanism.
- Molecular BiologyPLoS GeneticsPeer-reviewed
Human cells contain myriad excised linear intron RNAs with links to gene regulation and potential utility as biomarkers
Jun Yao, Hengyi Xu, Elizabeth A. Ferrick-Kiddie…·Alan M. Lambowitz
The paper identifies thousands of FLEXIs in human cells, links them to RNA-binding proteins, and suggests their potential as biomarkers.
7 citations - Genetic & Genomic MedicinemedRxivPreprint
TGIRT-seq of Inflammatory Breast Cancer Tumor and Blood Samples Reveals Widespread Enhanced Transcription Impacting RNA splicing and Intronic RNAs in Plasma
Dennis Wylie, Xiaoping Wang, Jun Yao…·Alan M. Lambowitz
This study uses TGIRT-seq to analyze IBC tumor and blood samples, revealing widespread transcriptional changes and RNA splicing impacts in plasma.
5 citations - GenomicsScientific ReportsPeer-reviewed
Improved TGIRT-seq methods for comprehensive transcriptome profiling with decreased adapter dimer formation and bias correction
Hengyi Xu, Jun Yao, Douglas C. Wu, Alan M. Lambowitz
The paper improves TGIRT-seq methods by reducing adapter dimer formation and correcting 5- and 3-end biases, enhancing transcriptome coverage and library construction efficiency.
75 citations