Jonathan Z. Li

This study examines immune responses in adults with COVID-19 who received or did not receive nirmatrelvir-ritonavir, finding no differences in immune markers between those with and without virologic rebound.

This study identifies a new form of nonsuppressible viremia in HIV patients on ART, linked to macrophage tropism and genetic diversity, distinct from previously known CD4+ T cell-related NSV.

The paper examines transcriptional changes in adipose tissue from subacute COVID-19 and Long COVID patients, finding no persistent viral RNA but significant transcriptional remodeling in subacute cases and no consistent gene expression differences in Long COVID.

The paper models viral rebound after nirmatrelvir-ritonavir treatment, finding that target cell preservation and incomplete viral clearance drive rebound, with extended treatment reducing this risk.

This study shows that SARS-CoV-2 mAb treatment shifts memory B cell epitope recognition, affecting their response to vaccination.

This paper models viral resistance emergence in SARS-CoV-2 treated with anti-spike monoclonal antibodies, showing that target cell replenishment mechanisms can explain high viral rebounds.

The paper examines placental ACE2 and TMPRSS2 expression in relation to maternal SARS-CoV-2 infection and fetal sex, finding sexually dimorphic effects on TMPRSS2 but not ACE2.

The paper develops a rapid, sensitive, and scalable isothermal amplification method for detecting SARS-CoV-2 from patient samples.

The paper identifies two SARS-CoV-2 genome loci associated with increased COVID-19 mortality risk using logistic regression on whole-genome sequencing data.

This study analyzes viral rebound kinetics after immunotherapy in HIV/SIV, finding that vaccines and TLR7-agonists reduce latent reservoir reactivation and boost immune responses.