ImmunologyPLoS PathogensPeer-reviewed
Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody
Tin Phan, Carolin Zitzmann, Kara W Chew…·the ACTIV-2/A5401 Study Team
This paper models viral resistance emergence in SARS-CoV-2 treated with anti-spike monoclonal antibodies, showing that target cell replenishment mechanisms can explain high viral rebounds.
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