BiophysicsbioRxivPreprint
ATP energy-independentlymodulates the folding equilibrium of ALScausing C71G-hPFN1
Jian Kang, Liangzhong Lim, Jianxing Song
This study investigates how ATP modulates the folding equilibrium of the ALS-causing C71G-hPFN1 mutant, revealing its role in inducing folding, inhibiting aggregation, and increasing stability.
DOI 10.1101/2023.08.24.554696