Vasily V. Grinev

The paper compares classical and machine learning algorithms for identifying single nucleotide polymorphisms using simulated data, finding CART as the most effective method.

ORFhunteR is a tool that accurately identifies and annotates open reading frames in human mRNA molecules using a random forest classifier trained on RefSeq and Ensembl data.

The paper identifies unisplice and multisplice splice sites in leukemia cells and shows their combinatorics follow a power-law, revealing hidden multisplice potential in unisplice sites.

This study identifies two mechanisms by which RUNX1/RUNX1T1 regulates alternative splicing in t(8;21)-positive acute myeloid leukemia cells, affecting RNA isoform production and protein structure.