Volker Ellenrieder

Deep proteomics of 997 treatment-naïve colorectal cancers defines six subgroups, splitting chromosomally unstable tumors into three and revealing a rare adverse subgroup, with H&E slide benchmarks.

This study benchmarks decontamination methods for intratumoral microbiome analysis in PDAC, finding the Nj pipeline outperforms others in reducing contamination while preserving tumor signals.

The paper identifies AP1 transcription factor dichotomy and CD68+ macrophages as drivers of intratumoral subtype co-existence and therapy response in pancreatic cancer.

The paper develops a single-nucleus full-length RNA-sequencing approach to identify intronic variants linked to mis-splicing in pancreatic cancer.

This study shows that neutrophil-derived complement factor P induces apoptosis in basal-like pancreatic cancer cells via caspase 3/7 activation, linking properdin expression to better prognosis.