Maximilian Ackermann

This study maps venous remodelling in IPF using multiscale imaging and molecular data, showing venous enlargement correlates with disease severity and poor survival.

This paper identifies PDE3A-SLFN12 molecular glues as a novel therapeutic target for KIT D816V-driven mast cell malignancies, showing their efficacy in killing multiple KIT D816V cell types and synergy with tyrosine kinase inhibitors.

This paper presents the first single-nucleus RNA sequencing atlas of pleuroparenchymal fibroelastosis, identifying novel cell states and their spatial organization in lung fibrosis.

The Human Organ Atlas provides open access to multiscale 3D imaging of human organs, along with tools and resources for analysis and research.

The paper develops a multiscale segmentation pipeline using HiP-CT and deep learning to identify glomeruli in human kidneys across different resolutions.

This paper demonstrates the application of Hierarchical Phase-Contrast Tomography (HiP-CT) in three biomedical case studies, revealing detailed organ structures at multiple scales.

This study identifies JAK2V617F zygosity-specific vascular changes in MPN and shows IFNα inhibits EndMT, offering a novel antifibrotic mechanism.

This paper demonstrates HiP-CT's ability to image adult human hearts at multiple scales, revealing structural details in health and disease.