ImmunologyAtherosclerosisPeer-reviewed
Atheroma plaque microenvironment stimulates kynurenine production by macrophages to induce endothelial adhesion molecules in the context of atherogenesis
Kévin Van Dongen, Damien Leleu, Thomas Pilot…·Thomas Gautier
This study shows that atheroma plaque microenvironment activates the kynurenine pathway in macrophages, increasing kynurenine production which induces endothelial adhesion molecules, promoting atherogenesis.
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