Developmental BiologyNature CommunicationsPeer-reviewed
Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness
Bess P. Rosen, Qing V. Li, Hyunwoo Cho…·Danwei Huangfu
The paper uses CRISPR-Cas9 screens to identify genes affecting stem cell fitness versus pluripotency identity, finding distinct and overlapping roles for chromatin and metabolic regulators.
15 citations